Science News

Emergence of the Middle East Respiratory Syndrome Coronavirus

Christopher M. Coleman and Matthew B. Frieman*

Vincent Racaniello, Editor

Author information ? Copyright and License information ?

This article has been cited by other articles in PMC.

Introduction

It began routinely enough. A patient with severe respiratory disease at the Dr. Soliman Fakeeh Hospital in Jeddah,... Read More

More About Plasma Renin And Cardiovascular Mortality

Michael H. Alderman, John H. Laragh, Jean E. Sealey

DOI: http://dx.doi.org/10.1093/eurheartj/ehr187 2610-2612 First published online: 30 June 2011

This editorial refers to ‘Association of plasma renin with 10-year cardiovascular mortality, sudden cardiac death, and death due to heart failure’†... Read More

Macam - Macam Luka Dan Penanganannya

Pengertian Luka

Luka adalah rusaknya kesatuan/komponen jaringan, dimana secara spesifik terdapat substansi jaringan yang rusak atau hilang.

Ketika luka timbul, beberapa efek akan muncul :

1. Hilangnya seluruh atau sebagian fungsi organ

2. Respon stres simpatis

3. Perdarahan dan pembekuan darah

4. Kontaminasi bakteri

5. Kematian sel

Jenis Luka:

1.   Berdasarkan Tingkat Kontaminasi Luka.

Luka Bersih (Clean Wounds). Yang dimaksud dengan luka bersih adalah luka bedah tak terinfeksi yang mana luka tersebut... Read More

Tren Penyakit Cardiovascular di Eropa tahun 2014

Melanie Nichols1,2, Nick Townsend1*, Peter Scarborough1, and Mike Rayner1

1British Heart Foundation Centre on Population Approaches for Non-Communicable Disease Prevention, Nuffield Department of Population Health, University of Oxford,

Old Road Campus, Oxford OX3 7LF, UK; and 2Population Health Strategic Research Centre, Faculty of Health, Deakin University, Geelong, Australia

Makalah ini memberikan update penyakit kardiovaskular (CVD) 2014, dan penyakit tertentu jantung koroner (PJK) dan stroke, di negara-negara Eropa. Penyakit kardiovaskular menyebabkan lebih banyak kematian di antara orang Eropa daripada kondisi  lainnya, dan di banyak negara masih menyebabkan kematian  dua kali lebih  banyak dari pada kematian akibat  kanker. Ada bukti jelas... Read More

Treatment of Elevated Cholesterol
   Benjamin M. Scirica, MD;     Christopher P. Cannon, MD

+Author Affiliations

From the TIMI Study Group, Cardiovascular Division, Brigham and Women’s Hospital, Boston, Mass. Correspondence to Dr Benjamin Scirica, TIMI Study Group, Cardiovascular Division, Brigham... Read More
JURNAL EROPA TENTANG PERNAPASAN , JURNAL ILMIAH RESMI TENTANG ERS

PENYAKIT PERNAPASAN ANAK PADA MASA LALU, SEKARANG DAN NANTI

Penyakit pernapasan pediatri atau penyakit pernapasan pada anak-anak  telah berubah dalam kurun waktu 20 tahun terakhir. Kita dapat berpartisipasi untuk membuat kemudian menerbitkan penelitian kita dalam jurnal yang berbayar kepada pemilik jurnal. Kita bisa memberikan tantangan baru kepada rekan kerja dalam ranah penyakit pernapasan pada orang dewasa. Banyak orang-orang dewasa juga harus mempelajari kondisi yang 20 tahun lalu jarang ditemui di klinik, tentang penyakit yang menyerang bagian dada manusia seperti penyakit fibrosis kistik (CF) dan konsekuensi jangka panjang pada kelahiran bayi yang prematur dan cacat bawaan pada saluran pernapasannya. Kemudian dilanjutkan dengan pembelajaran dini untuk... Read More

Jurnal internasional Mengenai Perawatan Kecantikan dan Anti Penuaan

Ilmu pengetahuan tentang perawatan kulit  

Ditulis oleh Ivana Veljkovic / diterbitkan oleh 'Tropikal Treatments' pada tanggal  31 juli 2014  

Sehubungan dengan meningkatnya jumlah produk perawatan kulit di pasaran, Ivana Veljkovic memberikan  informasi  mengenai bahan dan komponen yang dibutuhkan untuk membuat formulasi yang tepat.   Seiring berkembangnya pengetahuan mengenai formulasi perawatan kulit, para ahli kecantikan kemudian menemukan cara baru dan  inovatif untuk menciptakan  produk yang... Read More

AJG (The American Journal Of Gastroenterology Supplements)

Original Contribution

Am J Gastroenterol Suppl (2012) 1:34–40; doi:10.1038/ajgsup.2012.7

Using Probiotics in Gastrointestinal Disorders

Yehuda Ringel MD, FACG1, Eamonn MM Quigley MD FACG2 and Henry C Lin MD3

1Division of Gastroenterology and Hepatology, Department of Medicine, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA

2Alimentary Pharmabiotic Center, Department of Medicine, University College Cork, Cork, Ireland

3Section of Gastroenterology, New Mexico VA Health Care System and University of New Mexico, Albuquerque, New Mexico, USA

Correspondence: Yehuda Ringel, MD, FACG, Division of Gastroenterology and Hepatology, Department of Medicine,... Read More

Erectile Dysfunction

Kevin T. McVary, M.D.

N Engl J Med 2007; 357:2472-2481December 13, 2007DOI: 10.1056/NEJMcp067261

A 65-year-old man presents to an outpatient clinic, reporting that he can no longer maintain an erection sufficient for intercourse. His medical history includes well-controlled hypertension and stable coronary artery disease. He smokes a pack of cigarettes daily. His medications include atenolol and low-dose aspirin (81 mg daily). On physical examination, his body-mass index (the weight in kilograms divided by the square of the height in meters) is 31; the examination is otherwise unremarkable, with normal external genitalia and no loss of body hair. How should he be evaluated and treated?

THE CLINICAL PROBLEM

Erectile dysfunction is defined as... Read More

MENJAGA KESEHATAN DI BULAN PUASA

Tidak terasa kita sudah memasuki bulan ramadhan dimana umat Islam selalu menantikan bulan tersebut, bulan yang suci dimana setiap kegiatan yang bernilai pahala akan dilipatgandakan pahalanya dan salah satunya adalah puasa.  Menjaga kesehatan tubuh saat berpuasa memang harus diperhatikan. Pasalnya, ketika bulan Ramadhan datang dan menjalani puasa, kita banyak mengalami perubahan dalam pola hidup dan pola makan. Menjalani puasa Ramadhan memang sudah wajib hukumnya, akan tetapi kita juga harus tetap menjaga kesehatan ketika puasa agar jangan sampai sakit ketika hari raya tiba.

Agar aktivitas pada bulan puasa dapat berjalan normal seperti hari-hari biasa,... Read More

BERHENTI MEROKOK

PENDAHULUAN

Kebiasaan merokok mempunyai dampak yang buruk terhadap kesehatan terutama pada organ paru-paru dan pernafasan. Berbagai penyakit paru  timbul akibat rokok antara lain kanker paru dan penyakit paru obstruktif kronik (PPOK). Di Indonesia prevalensi perokok makin meningkat tidak saja laki-laki namun juga pada perempuan. Yang lebih memprihatinkan makin banyak perokok sudah dimulai pada usia yang  sangat dini.

Selain itu rokok juga memberikan bahaya bagi orang yang berada sekitar perokok. Hal ini penting karena lebih dari 85% perokok... Read More

PNEUMONIA

Pneumonia adalah penyakit saluran napas bawah (lower respiratory tract (LRT)) akut, biasanya disebabkan oleh infeksi (Jeremy, 2007). Insidensi tahunan: 5-11 kasus per 1.000 orang dewasa; 15-45% perlu di rawat dirumah sakit (1-4 kasus), dan 5-10% diobati di ICU. Insidensi paling tinggi pada pasien yang sangat muda dan usia lanjut. Mortalitas: 5-12% pada pasien yang dirawat di rumah sakit; 25-50% pada pasien ICU (Jeremy, 2007). Di Amerika, insidensi untuk penyakit ini mencapai 12 kasus tiap 1.000 orang dewasa. Kematian untuk pasien rawat jalan kurang dari 1%, tetapi kematian pada pasien yang dirawat di rumah sakit cukup tinggi yaitu sekitar 14% (Alberta Medical Association, 2002). Di negara berkembang sekitar 10-20% pasien yang memerlukan perawatan di rumah sakit dan angka kematian diantara... Read More

Technique to Detect Breast Cancer in Urine Developed

May 23, 2013 — A Missouri University of Science and Technology researcher has developed a new screening method that uses urinalysis to diagnose breast cancer -- and determine its severity -- before it could be detected with a mammogram. A study to confirm this technique's effectiveness is under way at Mercy Breast Center in Springfield, Mo.

 

Dr. Yinfa Ma, Curators' Teaching Professor of chemistry at Missouri S&T, uses a device called a P-scan, to detect the concentration of certain metabolites called pteredines in urine samples. These biomarkers are present in the urine of all human beings, but abnormally high concentrations can signal the presence of cancer. Ma believes the levels continue to rise as the... Read More

Skin Cancer May Be Linked to Lower Risk of Alzheimer's Disease

May 15, 2013 — People who have skin cancer may be less likely to develop Alzheimer's disease, according to new research published in the May 15, 2013, online issue of Neurology®, the medical journal of the American Academy of Neurology. The link does not apply to melanoma, a less common but more aggressive type of skin cancer.

The study involved 1,102 people with an average age of 79 who did not have dementia at the start of the study. The participants were followed for an average of 3.7 years. At the start of the study, 109 people reported that they had skin cancer in the... Read More

Novel Mechanism by Which UVA Contributes to Photoaging of Skin

Apr. 25, 2013 — A study conducted by researchers at Boston University School of Medicine (BUSM) provides new evidence that longwave ultraviolet light (UVA) induces a protein that could result in premature skin aging. The findings demonstrate that aspects of photoaging, the process of skin aging by chronic exposure to ultraviolet radiation, could be linked to genetic factors that accelerate the aging process when induced by the environment.

 

The study, published in the Journal of Investigative Dermatology, was led by BUSM co-authors Thomas M. Ruenger MD, PhD, professor and vice chair of the department of dermatology, and Hirotaka Takeuchi, MS.

Photoaging is attributed to continuous... Read More

New Class of Drug Targets Skin Cancer

May 7, 2013 — A new class of drug targeting skin cancer's genetic material has been successfully tested in humans for the first time, opening the way to new treatments for a range of conditions from skin cancers to eye diseases.

The research involves the drug Dz13, a targeted molecular therapy, which was developed at the University of New South Wales (UNSW) and has now been found to be safe in a clinical trial of patients with the common skin cancer, basal-cell carcinoma.

"This is the first report of a drug of this type to be used in humans," says UNSW Medicine's Professor... Read More

New Agent Might Control Breast-Cancer Growth and Spread

Apr. 22, 2013 — A new study led by researchers at The Ohio State University Comprehensive Cancer Center -- Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC -- James) suggests that an unusual experimental drug can reduce breast-cancer aggressiveness, reverse resistance to the drug fulvestrant and perhaps improve the effectiveness of other breast-cancer drugs.

The drug AS1411 works by blocking the cell's production of regulatory molecules called microRNA, some types of which are associated with cancer. Specifically, the drug inhibits a protein called nucleolin... Read More

Nanotechnology

Nanotechnology refers broadly to a field of applied science and technology whose unifying theme is the control of matter on the molecular level in scales smaller than 1 micrometre, normally 1 to 100 nanometers, and the fabrication of devices within that size range. It is a highly multidisciplinary field, drawing from fields such as applied physics, materials science, colloidal science, device physics, supramolecular chemistry, and even mechanical and electrical engineering.

 

Much speculation exists as to what new science and technology may result from these lines of research.

Nanotechnology can be seen as an extension of existing sciences into the nanoscale, or as a recasting of existing sciences using a newer,... Read More

Discovery Helps Show How Breast Cancer Spreads

May 5, 2013 — Researchers at Washington University School of Medicine in St. Louis have discovered why breast cancer patients with dense breasts are more likely than others to develop aggressive tumors that spread. The finding opens the door to drug treatments that prevent metastasis.

Researchers at Washington University School of Medicine in St. Louis have discovered why breast cancer patients with dense breasts are more likely than others to develop aggressive tumors that spread. The finding opens the door to drug treatments that prevent metastasis. It has long been known... Read More

Western Style Diet May Lead to Greater Risk of Premature Death

Following a Western Style Diet May Lead to Greater Risk of Premature Death

 

Apr. 15, 2013 — Data from a new study of British adults suggest that adherence to a "Western-style" diet (fried and sweet food, processed and red meat, refined grains, and high-fat dairy products) reduces a person's likelihood of achieving older ages in good health and with higher functionality. Study results appear in the May issue of The American Journal of Medicine

"The impact of diet on specific age-related diseases has been studied extensively, but few investigations... Read More

Scientists Find Interferon

Scientists Find Interferon, One of the Body's Own Proteins, Induces Persistent Viral Infection

Apr. 9, 2013 — Scientists at The Scripps Research Institute (TSRI) have made a counterintuitive finding that may lead to new ways to clear persistent infection that is the hallmark of such diseases as AIDS, hepatitis B and hepatitis C.

 

 

Illustration. “Our findings illuminate an unexpected role for IFN-I protein(s) in persistent infections, which has major implications for how we treat these infections,” said Michael B. A. Oldstone (Credit: Image courtesy of... Read More

Pain Relief With PAP Injections May Last 100 Times Longer Than a Traditional Acupuncture Treatment

 

Pain Relief With PAP Injections May Last 100 Times Longer Than a Traditional Acupuncture Treatment

Apr. 23, 2012 — Scientists at the University of North Carolina at Chapel Hill have identified a new way to deliver long-lasting pain relief through an ancient medical practice.

PAP (red) is found in neurons that sense pain-producing stimuli. (Credit: Zylka lab, UNC-Chapel Hill.)

 

In an article published in the April 23 online edition of Molecular Pain, UNC researchers describe how exploiting the molecular mechanism behind acupuncture resulted in six-day pain relief... Read More

Implantable, Bioengineered Rat Kidney

 

Implantable, Bioengineered Rat Kidney: Transplanted Organ Produces Urine, but Further Refinement Is Needed

Apr. 14, 2013 — Bioengineered rat kidneys developed by Massachusetts General Hospital (MGH) investigators successfully produced urine both in a laboratory apparatus and after being transplanted into living animals. In their report, receiving advance online publication in Nature Medicine, the research team describes building functional replacement kidneys on the structure of donor organs from which living cells had been stripped, an approach previously used to create bioartificial hearts, lungs and livers.

... Read More

Current HPV Vaccine May Not Help Some Women With Immune Problems

Current HPV Vaccine May Not Help Some Women With Immune Problems

Apr. 7, 2013 — Women with HIV acquire cancer-causing forms of the human papillomavirus (HPV) that are not included in the current HPV vaccines Gardasil and Cervarix, according to new research from Fox Chase Cancer Center being presented at the AACR Annual Meeting 2013 on Sunday, April 7.

 

"People with issues in their immune system such as HIV will be at risk of acquiring HPV, as well -- and the current vaccine may not fully protect them," says study author Elizabeth Blackman, MPH, research specialist at Fox Chase.

Women who had been taking HIV medications for at least 4 years, however, were less likely to carry cancer-causing forms of HPV, suggesting... Read More

Constructing a Medical Nanobot - Peptide Nanofibers For Cardiac Ischemic Damage Repair

Constructing a Medical Nanobot - Peptide Nanofibers For Cardiac Ischemic Damage Repair

James Robb, MD, Pathology, 07:22AM Mar 28, 2013

Dear Colleagues, many of us have or will be involved with ischemic heart disease, either personally or with our families, friends, and patients. It is a very significant global health problem. A promising approach to decreasing the morbidity and mortality from this disease is to promote the rapid revascularization of the damaged cardiac tissue. This post will discuss the recent work with peptide nanofibers (NF) in combination with endothelial growth factor (VEGF) in both rat and pig models. This nanoprocess is a promising treatment of acute ischemic heart disease, using a simple nanobot - self assembling, drug carrying, nanofibers injected... Read More

What's All That Noise

... Read More

The importance of phospholipid in Regenerative Medicine

Prof.Dr.Habil.Claus Muss Ph.D

International Research Group For Preventive Medicine Vienna, Austria.Phospholipid is the type of lipid which is a major component of all cell membranes, which form a layer of fat bilayer. Many of the phospholipids consist of diglyceride, phosphate group, small organic molecules such as choline. Phospholipid that was first identified in biological tissues is lecithin or phosphatidylcholine, in the yolk. The structure of the phospholipid molecules are generally composed of a hydrophobic chain and hydrophilic head. These are usually found along with cholesterol molecules are found among the empty space of phospholipids.

Head is... Read More

Mobile Phone Could Make a Man of Infertility?

Be careful of men, especially the unusual long separated from his cell phone. Recent research states that this sophisticated communications equipment that can damage your sperma.Jika is the kind of person who likes to keep a cell phone (mobile) in a pants pocket or included in a small holster and hung at the waist, then your sperm count and quality can be reduced by 30% . Radiation emitted by mobile phones negative effect on sperm production and male fertility. The statement disclosed by researchers from the Department of Obstetrics and Gynecology, University of Szeged, Hungary, which also reported the results of his research in a conference of The European Society of Human Reproduction and Embryology in Berlin, Germany.In their study, the researchers analyzed the sperm... Read More

ANTI-AGING MEDICINE IN DAILY PRACTICE (Prof. Dr. dr. Wimpie Pangkahila, Sp.And)

Introduction 

In Common sense, people believe that getting old is destiny that should not and can not be intervented. Peolple believe that getting old is a part of life cycle that must bepassed through with no argue. Even there is a common belief that human age has already been defined by the Almighty God and it is not negotiable.However, the diffirence in life expectancy between people in different countries has demostrated that there must be something that makes the difference. Developed countries generally have more number of helathy aging people compared to developing, moreover underdeveloped countries.The development in basic and clinical researches demonstrated that aging process can be slowed down , delayed even reserved. The result is lifespan... Read More

Calcium Supplements and Risk of Myocardial Infarction: An Hypothesis Twice Tested

Hennekens and Barice suggest that the work we have published linking calcium supplements to risk of myocardial infarction is merely hypothesis-generating, and needs to be balanced against the “fact” that “calcium is essential … for the prevention of osteoporosis.” The authors suggest that this hypothesis was based on our 2010 meta-analysis, but it actually arose from the unexpected findings of the Auckland Calcium Study published in 2008. The 2010 meta-analysis tested the a priori hypothesis that calcium supplements increased the risk of myocardial infarction and showed a consistent adverse effect across the major randomized, controlled trials. We have now demonstrated the same consistent adverse effect in treatment-naive subjects randomized to calcium with... Read More

Antifungal Drug Resistance: Mechanisms, Epidemiology, and Consequences for Treatment

Abstract 

Antifungal resistance continues to grow and evolve and complicate patient management, despite the introduction of new antifungal agents.

In vitro susceptibility testing is often used to select agents with likely activity for a given infection, but perhaps its most important use is in identifying agents that will not work, i.e., to detect resistance.

Standardized methods for reliable in vitro antifungal susceptibility testing are now available from the Clinical and Laboratory Standards Institute (CLSI) in the United States and the European Committee on Antimicrobial Susceptibility Testing (EUCAST) in Europe.

Data gathered by these standardized tests are useful (in conjunction with other forms of data) for calculating clinical... Read More

A cousin of a molecule that stimulates eyelash growth may stop hair growth on the scalp

A protein called prostaglandin D2 (green) is made by cells in human hair follicles like this one. A new study shows that the protein inhibits stem cells (red) needed to make hair grow. Courtesy of Luis Garza and George Cotsarelis

Just because a man is bald doesn’t mean there’s nothing going on in his scalp. A molecule found in the scalps of bald men may offer clues about how male pattern baldness arises and what to do about it.Men with male pattern baldness have higher levels of a molecule called prostaglandin D2 in the bald parts of their scalps than in parts still covered in hair, a new study shows. Prostaglandin D2 stops the growth of stem cells that give rise to hair follicles, stem cell biologist George Cotsarelis of the Perelman Center for Advanced Medicine... Read More

Daily aspirin 'prevents and possibly treats cancer'

Taking a low dose of aspirin every day can prevent and possibly even treat cancer, fresh evidence suggests. The three new studies published by The Lancet add to mounting evidence of the drug's anti-cancer effects. Many people already take daily aspirin as a heart drug.

But experts warn that there is still not enough proof to recommend it to prevent cancer cases and deaths and warn that the drug can cause dangerous side effects like stomach bleeds.Prof Peter Rothwell, from Oxford University, and colleagues, who carried out the latest work, had already linked aspirin with a lower risk of certain cancers, particularly bowel cancer.But their previous work suggested people needed to take the drug for about 10 years to get any protection.Now the same experts believe... Read More

Transplanted Neurons Curb Obesity

Immature neurons transplanted into the brains of obesity-prone mice can prevent the animals from becoming so fat, according to a new study. The researchers caution that their experiment was never intended as a step toward treating obesity in humans, but they say it provides an important proof of principle that transplanted fetal cells can integrate themselves into an abnormal neural circuit and help restore its function. Other researchers say the work highlights both the promise and the challenges of developing cell therapies for complex brain disorders.

The road to fetal or stem cell therapies for the nervous system has been rocky. Despite early promise, recent trials of fetal cell transplants for Parkinson's disease have yielded disappointing results, for example, and last week... Read More

Alzheimer's damage reversed by deep brain stimulation

BRAIN shrinkage in people with Alzheimer's disease can be reversed in some cases - by jolting the degenerating tissue with electrical impulses. Moreover, doing so reduces the cognitive decline associated with the disease.

"In Alzheimer's disease it is known that the brain shrinks, particularly the hippocampus," says Andres Lozano at Toronto Western Hospital in Ontario, Canada. What's more, brain scans show that the temporal lobe, which contains the hippocampus, and another region called the posterior cingulate use less glucose than normal, suggesting they have shut down. Both regions play an important role in memory.

To try to reverse these degenerative effects, Lozano and his team turned to deep brain stimulation - sending electrical impulses to the brain via implanted electrodes.

The... Read More

Key to Aging? Key Molecular Switch for Telomere Extension by Telomerase Identified

Researchers at the University of Illinois at Chicago College of Medicine describe for the first time a key target of DNA damage checkpoint enzymes that must be chemically modified to enable stable maintenance of chromosome ends by telomerase, an enzyme thought to play a key role in cancer and aging.

Their findings are reported online in Nature Structural and Molecular Biology.

Telomeres are the natural ends of chromosomes, consisting of specialized DNA-and-protein structures that protect chromosome ends and ensure faithful duplication of chromosomes in actively dividing cells. An essential player in telomere maintenance is an enzyme complex called telomerase. Without telomerase, telomeres become progressively shorter each time the cell divides.

If telomeres become... Read More

Cancer's sweet tooth maybe its weak link

Researchers at Albert Einstein College of Medicine of Yeshiva University have discovered that cancer cells tap into a natural recycling system to obtain the energy they need to keep dividing. In a study with potential implications for cancer treatments, Einstein researchers used genetic manipulation to turn off this recycling system within the walls of cells and stop both tumor growth and metastasis (cancer spread).

The findings were published in today's online edition of Science Translational Medicine.

Scientists have known that cancer cells require a large amount of energy in the form of glucose (sugar) to support their abnormally rapid growth. But it wasn't clear how cancer cells met those energy needs. The study shows that cancer cells fuel their growth by revving... Read More

Biosensor can monitor your heartbeat from a distance

A new type of sensor can continuously monitor your heart rate without actually touching you.

The chip, known as the Electric Potential Integrated Circuit (EPIC) biosensor, is essentially a super-sensitive digital voltmeter which can measure tiny changes in electrical fields around all muscles and nerves.

The final product will be integrated into hospital beds, from where it will unobtrusively monitor a patient's vital signs, doing away with pesky tubes, leads and wires. It can track movement not only in heart muscles, but also muscles in the lungs, limbs and eyes.

The sensor's special twist is a filtering technology which isolates and spits out the exact measurement you want. So, if you're looking for eyeball movements, the sensor will comply, without confusing you... Read More

Exceptional memory linked to bulked-up parts of brain

People who can recall life’s events in detail have enlarged region linked to obsessive-compulsive disorder

WASHINGTON — Like the fictional detective Carrie Wells on the TV show Unforgettable, some real-life people can remember every day of their lives in detail. Those superrememberers have more bulk in certain parts of their brains, possibly explaining the remarkable ability to recall minutiae from decades ago, researchers said November 13 at the annual meeting of the Society for Neuroscience.

One brain region involved in such incredible recall has been implicated in obsessive-compulsive disorder, hinting that OCD and superior memory might have a common architecture in the brain.

Scientists have long studied people with memory deficits, but there... Read More

UAMS Researchers Find Critical Clue to Bone Renewal Process

Researchers from the University of Arkansas for Medical Sciences (UAMS) seeking to isolate the cellular trigger for the constant bone renewal process in the skeleton found that cells embedded within the bone are an unexpected source of a protein that is a key player in the process.

Understanding the ongoing cellular processes of bone destruction and renewal, called bone remodeling, could lead to new treatments for diseases such as bone-weakening osteoporosis.

The team, led by Charles O’Brien, Ph.D., a professor in the UAMS College of Medicine and a scientist in the UAMS Center for Osteoporosis and Metabolic Bone Diseases, reported that a unique type of cell in the bone appeared to be the catalyst in the bone renewal process — and not other cell types widely believed... Read More

Lasker Awards Honors for Studies of Protein Folding, Malaria Drug

Two scientists who discovered a cell "machine" involved in protein folding and a researcher who found a life-saving treatment for malaria are this year's recipients of the Albert and Mary Lasker Foundation's Lasker Awards, which are among the most prestigious prizes in biomedical research.

Biochemist Franz-Ulrich Hartl, 54, of the Max Planck Institute of Biochemistry in Martinsreid, Germany, and biologist Arthur Horwich, 60, of Yale University share this year's prize for basic medical research. In the late 1980s, they discovered that although a linear string of amino acids can fold into its proper three-dimensional shape in a test tube, the protein cannot do this on its own within a cell. Instead, a cagelike molecular apparatus dubbed a chaperonin wraps itself around the nascent... Read More

Low Vitamin D Common in Spine Surgery Patients Deficiency May Hinder Recovery

A new study indicates that many patients undergoing spine surgery have low levels of vitamin D, which may delay their recovery.

In a study of 313 patients undergoing spinal fusion surgery, orthopaedic surgeons at Washington University School of Medicine in St. Louis found that more than half had inadequate levels of vitamin D, including one-fourth who were more severely deficient.

The researchers report their findings at the 26th Annual Meeting of the North American Spine Society. The study was chosen as one of the meeting's best papers.

"Our findings suggest it may be worthwhile to screen surgery patients for vitamin D," says Jacob M. Buchowski, MD, the study's principal investigator. "We think those with insufficient levels of vitamin D may benefit from taking 50,000... Read More

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